Sugammadex vs Neostigmine for Reversal of Neuromuscular Blockade and Association with Postoperative Atelectasis After Video-Assisted Thoracoscopic Surgery: A Propensity Score-Matched Cohort Study - Pu
5 hours ago
- #atelectasis
- #sugammadex
- #VATS
- Study compares sugammadex and neostigmine for reversing neuromuscular blockade in VATS patients.
- Sugammadex linked to lower odds of postoperative atelectasis (OR 0.79, 95% CI 0.72-0.86).
- Absolute risk reduction of 3.3% for atelectasis with sugammadex (15.3% vs 18.6%).
- Benefits consistent at 7-day and 90-day follow-ups.
- Sugammadex also associated with reduced pneumothorax (OR 0.90) and MACEs (OR 0.75).
- No significant association with pneumonia, respiratory failure, or sepsis.
- Subgroup analyses show stronger effects in males and non-obese patients.
- Prospective trials needed to confirm causality.