Isolation, identification, and molecular characterization of Streptococcus mutans and Enterococcus faecalis from dental caries - PubMed
6 hours ago
- #Postbiotics
- #Antibiotic Resistance
- #Dental Caries
- The study isolated 83 bacterial strains from severe dental caries: 59 Streptococcus mutans and 24 Enterococcus faecalis.
- Antibiotic susceptibility testing showed high resistance to gentamicin (100%) and erythromycin (65-70%), with consistent sensitivity to penicillin, tetracycline, vancomycin, and clindamycin.
- Postbiotic extracts from Limosilactobacillus plantarum GD29 inhibited S. mutans biofilm formation in a dose-dependent manner, achieving up to 78% reduction at 50% (v/v) concentration.
- Findings support the potential of postbiotics as alternative therapeutic agents for managing cariogenic biofilms and highlight the need for targeted strategies against antibiotic resistance.