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Efficacy of HMB supplementation as an adjunct to resistance training in older adults: a comprehensive meta-analysis - PubMed

6 hours ago
  • #older adults
  • #HMB supplementation
  • #resistance training
  • HMB supplementation combined with resistance training does not significantly improve fat mass, muscle mass, or muscle strength in adults aged 50+.
  • Meta-analysis of 13 RCTs involving 561 participants found no advantageous effects, with SMDs close to zero and confidence intervals spanning negligible benefits.
  • Low heterogeneity for body composition outcomes but high heterogeneity for strength measures; no publication bias was detected.
  • HMB supplementation is not recommended as a routine adjunct to resistance training for older adults capable of structured exercise.