Long-Term Cardiovascular and Noncardiovascular Mortality After Acute Coronary Syndrome: A Nationwide Competing-Risks Analysis of 1.56 Million Patients - PubMed
3 days ago
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- #acute coronary syndrome
- #competing risks
- Study investigates long-term cardiovascular (CV) and non-CV mortality after acute coronary syndrome (ACS) discharge.
- Analysis of 1.56 million patients from the China Cardiovascular Association Database-Chest Pain Center.
- CV death was the primary driver of mortality at 1-month discharge (1.24% vs 0.26% for non-CV).
- Non-CV mortality showed higher relative growth than CV mortality after 12-month discharge.
- Ischemic heart disease (68.5%) was the predominant CV death cause.
- Non-CV death was dominated by malignancy (38.3%) and chronic pulmonary disease (15.8%).
- Age ≥65 years, chronic kidney disease, and chronic heart failure were leading predictors of death.
- Lipid-lowering therapy was associated with lower risks of all-cause, CV, and non-CV death.
- Transition in post-ACS mortality from CV to non-CV causes over time, with malignancy emerging as the leading cause of late-term death.