Oxytocin, vasopressin, and their crosstalk in sexually-dimorphic psychiatric conditions - PubMed
5 hours ago
- #Oxytocin
- #Anorexia
- #Autism
- Autism spectrum disorder (ASD) and anorexia nervosa (AN) show opposite sex differences in prevalence.
- ASD is more common in males, while AN is more prevalent in females.
- Both disorders share clinical features like social impairments and atypical eating patterns.
- Comorbidity between ASD and AN is higher than expected, suggesting shared etiological factors.
- Oxytocin and vasopressin are neuropeptides involved in social and feeding behaviors and exhibit sexual dimorphism.
- These neuropeptides can interact with each other's receptors, producing overlapping and opposing effects.
- The review explores oxytocin and vasopressin's roles in ASD and AN to explain their co-occurrence despite opposite sex ratios.