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Dual clinical remission in patients treated with biologics for severe asthma and eosinophilic chronic rhinosinusitis - PubMed

5 hours ago
  • #Biologics
  • #Clinical Remission
  • #Eosinophilic Chronic Rhinosinusitis
  • Study evaluates dual clinical remission (CR) in patients with severe asthma (SA) and eosinophilic chronic rhinosinusitis (ECRS) treated with biologics.
  • 67 patients with both SA and ECRS were retrospectively analyzed after receiving biologics for ≥12 months.
  • CR for SA was achieved in 37% of patients, while CR for ECRS was achieved in 60%.
  • Dual CR (for both conditions) occurred in 25% of patients.
  • Predictors of dual CR included age ≥65 years and presence of nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD).
  • Biologics used included omalizumab, mepolizumab, benralizumab, dupilumab, tezepelumab, and combinations.