Burden of 33 malignant tumor groups in 5 socio-demographic index areas and 21 regions from 1990 to 2041 - PubMed

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The study used GBD 2021 data to analyze and project the global burden of 33 malignant tumor groups across 5 SDI areas and 21 regions from 1990 to 2041.
In 2021, malignant tumors caused 23.4 million new cases, 9.8 million deaths, and 251 million DALYs, ranking third globally for DALYs.
Tracheal, bronchus, and lung (TBL) cancer was the leading cause of cancer mortality overall and in males, while breast cancer led in females.
In high-SDI areas, malignant tumors were the top cause of DALYs, with TBL, colorectal cancer (CRC), and breast cancer as leading contributors.
Projections to 2041 show decreasing age-standardized incidence rates for stomach and esophageal cancers, but increases for CRC, breast, prostate, and other cancers.
Cancer burden varies by SDI level and gender, with high-SDI regions dominated by TBL and CRC, and lower-SDI regions facing more gender-specific and infection-related cancers.

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