Longitudinal associations between body fat mass and cardiovascular outcomes among Chinese children: mediation by cardiometabolic risk factors - PubMed
6 hours ago
- #childhood obesity
- #mediation analysis
- #cardiovascular health
- Childhood adiposity is linked to adverse cardiovascular changes.
- Higher baseline fat mass percentage (FMP) in children is associated with increased left ventricular (LV) measures and altered LV function over a 2-year period.
- Elevated FMP also correlates with higher vascular metrics like carotid intima-media thickness and pulse pressure index.
- Similar associations were found for fat mass index, visceral fat mass, and subcutaneous fat mass.
- Cardiometabolic risk factors such as blood pressure, HDL cholesterol, and insulin resistance mediate these associations.
- The study involved 1064 Chinese children aged 10-15 years from the Huantai Childhood Cardiovascular Health Cohort Study.