Molecular epidemiological and genetic variability of Salmonella isolates from the tropical mountainous region of southern China (2017-2024) - PubMed
12 hours ago
- #foodborne diseases
- #antimicrobial resistance
- #Salmonella enterica
- Study analyzed 384 Salmonella strains from 2,540 samples (2017-2024) in tropical mountainous regions of southern China.
- Predominant serovars: S. I 1,4 [5],12:i:- (ST34, 43.5%) in diarrheal patients; S. Enteritidis (ST11, 40%) in systemic infections.
- S. Typhimurium (ST19, 39.1%) and S. Enteritidis (ST11, 35.1%) were most common in food and environmental samples.
- High resistance rates to ampicillin (63.8%), tetracycline (62.7%), ciprofloxacin (17.7%), cefotaxime (16.4%), and ceftazidime (15.6%).
- 115 isolates (29.9%) were multidrug-resistant; six were tigecycline-resistant, two with tet(X4) genes on a hybrid plasmid.
- Virulence gene distribution varied; genes like mig-5, pefA-D, spvB-D were more prevalent in systemic infection strains.
- cdtB gene (typhoid toxin) found in 19 non-typhoidal strains.
- First comprehensive report on Salmonella prevalence and genetic dynamics in tropical mountainous regions of southern China.