Optimal Timing for Oral Anticoagulant Discontinuation and Prognosis After Successful Catheter Ablation for Atrial Fibrillation - PubMed
21 hours ago
- #catheter ablation
- #oral anticoagulants
- #atrial fibrillation
- Optimal oral anticoagulant (OAC) discontinuation timing after successful atrial fibrillation ablation is unclear; this study assessed adverse events to determine the best timing.
- Retrospective analysis of 2,448 patients post-ablation found thromboembolic risk increased at 4-5 months, while bleeding risk decreased with longer OAC discontinuation.
- The optimal discontinuation point was 8.1 months, maximizing net clinical benefit by balancing thromboembolic and bleeding risks, with no significant mortality difference.
- OAC discontinuation at 8.1 months associated with higher thromboembolic risk but reduced bleeding risk, supporting individualized risk assessment post-ablation.