Antiviral drug discovery and development: challenges and future directions - PubMed
4 hours ago
- #antiviral drugs
- #drug discovery
- #COVID-19
- The COVID-19 pandemic has accelerated antiviral drug discovery and development.
- Significant advancements include target-based strategies, mechanism-based approaches, and pharmacokinetic optimization.
- Artificial intelligence is increasingly used in protein structure prediction, drug target identification, and bioactivity forecasting.
- Nanotechnology has been crucial in drug delivery and vaccine development, such as lipid nanoparticles in mRNA vaccines.
- Future directions may include targeting membraneless organelles (liquid–liquid phase separation).