Recurrent aquaporin 4-immunoglobulin G-positive neuromyelitis optica spectrum disorder in a patient with long-standing rheumatoid arthritis: A case report - PubMed
17 hours ago
- #autoimmune disorders
- #neuromyelitis optica spectrum disorder
- #rheumatoid arthritis
- Aquaporin 4-IgG positive neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune condition affecting optic nerves and spinal cord.
- Co-occurrence of NMOSD and rheumatoid arthritis (RA) is rare, with only 15 cases reported globally.
- A 34-year-old woman with long-standing RA developed relapsing NMOSD, highlighting risk of misdiagnosis as stroke in autoimmune patients with neurological symptoms.
- The report examines shared immunopathological mechanisms and suggests integrated treatment strategies for managing both disorders.
- It emphasizes the need for prompt brain/spinal cord MRI and aquaporin 4-IgG testing in RA patients with optic neuritis, a gap in current guidelines.