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Clinical Features and Prognostic Significance of Pulmonary Metastases in Metastatic Hormone-sensitive Prostate Cancer - PubMed

2 hours ago
  • #lung metastases
  • #prognosis
  • #prostate cancer
  • Patients with metastatic hormone-sensitive prostate cancer (mHSPC) and lung-only metastases had lower initial PSA levels, Gleason scores, and less lymph node involvement.
  • The presence of lung metastases (LM) was associated with better overall survival compared to those without LM, especially in high-volume mHSPC cases.
  • High-volume disease patients classified due to LM had longer overall survival than other high-volume patients and similar survival to low-volume disease patients.
  • The incidence of lung metastases did not significantly differ based on the volume of bone metastases.
  • Current tumor volume classifications may need reevaluation to better guide treatment for mHSPC patients with lung metastases.