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The Dual Role of Extracellular Vesicles in Aging and Age-Related Diseases: Pathophysiology and Therapeutic Potential - PubMed

a day ago
  • #aging
  • #therapeutic-potential
  • #extracellular-vesicles
  • Aging is a complex process leading to loss of physiological integrity and increased risk of chronic diseases.
  • Extracellular vesicles (EVs) play a dual role in aging and age-related diseases, both contributing to pathology and offering therapeutic potential.
  • EVs from senescent or diseased cells propagate inflammation, oxidative stress, and other harmful processes.
  • EVs from stem cells or healthy tissues can restore balance, enhance function, and promote tissue repair.
  • EVs hold promise as diagnostic biomarkers and treatments for aging-related conditions, despite challenges like rapid clearance.