Early immune events during SARS-CoV-2 infection impact memory T and B cell responses - PubMed
4 hours ago
- #immune memory
- #longitudinal study
- #SARS-CoV-2
- Early immune events during SARS-CoV-2 infection influence the quality and durability of memory T and B cell responses.
- A study of 46 hospitalized COVID-19 patients linked early inflammatory proteins and co-stimulatory molecules to enhanced long-term memory immunity.
- Early markers like TNFSF11 and FLT3LG, which inhibit dendritic cell maturation, were associated with poorer memory immune outcomes.
- The research provides longitudinal insights into both innate and memory immunity, identifying predictors of durable antibody responses.