symptom patterns outside the rome iv consensus in eastern and western patients with a disorder of gut-brain interaction - PubMed
7 hours ago
- #DGBI
- #symptom patterns
- #Rome IV
- The study investigates symptom patterns in Eastern and Western patients with Disorders of Gut-Brain Interaction (DGBI) that extend beyond the Rome IV criteria.
- Using the Enhanced Asian Rome questionnaire (EAR4Q), 1074 DGBI patients were analyzed, identifying 10 distinct symptom groupings.
- Some symptom groupings align with Rome IV classifications, while others involve multiple anatomical regions, challenging the Rome framework.
- Key findings include symptom clusters like IBS-D triggered by meals, constipation, upper and lower GI symptoms, and meal-related pain and gas symptoms.
- The study concludes that DGBI symptom patterns are complex and often surpass the anatomical subdivisions of the Rome criteria.