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Meningococcal and pneumococcal carriage in children living with HIV: a multi-center prospective study from Türkiye (MENPHIV-TR study) - PubMed

8 hours ago
  • #HIV
  • #Molecular Surveillance
  • #Vaccination
  • Children living with HIV (CLHIV) in Türkiye had a low meningococcal carriage rate (3.8%) with non-groupable strains, compared to healthy controls (8.9%).
  • Pneumococcal carriage in CLHIV (28.7%) was similar to controls (23.9%), with a majority (65.2%) being PCV13 serotypes.
  • Longer time since the last PCV13 dose was associated with lower pneumococcal carriage, and vaccinated siblings showed a borderline protective effect.
  • The study supports sustained vaccination in at-risk groups, household-level immunization, and continued molecular surveillance for CLHIV.