Clostridioides difficile Infection Among Hospitalized Patients With Cancer - PubMed
5 hours ago
- #Cancer
- #Hospitalization
- #Clostridioides difficile
- Patients with cancer are at increased risk of Clostridioides difficile infection (CDI) due to factors like chemotherapy and frequent healthcare exposure.
- Study analyzed 32,083,671 cancer-related hospitalizations (2016-2022), finding CDI in 1.4% (450,360 cases).
- CDI was associated with higher in-hospital mortality (7.3% vs 4.5%) and greater need for critical care interventions.
- Patients with CDI had higher rates of kidney replacement therapy, mechanical ventilation, and vasopressor use.
- Mortality varied geographically, ranging from 6.4% in the Midwest to 8.5% in the Northeast.
- Findings highlight the need for targeted prevention and early intervention strategies in cancer patients.