Lysosomal cholesteryl ester hydrolysis drives white matter repair by reprogramming microglia into a novel reparative state - PubMed
10 hours ago
- #white matter repair
- #microglia
- #cholesteryl ester hydrolysis
- Lysosomal cholesteryl ester hydrolysis promotes white matter repair by reprogramming microglia into a reparative state.
- The study focuses on mechanisms of myelin regeneration and identifies a therapeutic target for demyelination diseases.
- Ethics approvals were obtained, and authors declare no competing interests, ensuring research integrity.