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Rethinking ethanol consumption and colorectal carcinogenesis: an insight from diet and gut microbiota - PubMed

5 hours ago
  • #gut microbiota
  • #colorectal cancer
  • #ethanol
  • Ethanol consumption is a significant modifiable risk factor for colorectal cancer (CRC).
  • Intestinal microbiota changes are observed in high alcohol consumers and during polyp progression to CRC.
  • Diet, microbiota, and host interactions play a key role in health and disease.
  • A pilot study in Asturias, Spain, analyzed data from individuals with intestinal polyps.
  • The paper critically evaluates mechanisms of alcohol-induced toxicity and its link to CRC.
  • Dietary fiber intake may modulate alcohol consumption and gut microbiota composition.
  • The work highlights advances and future challenges in understanding the diet-microbiota-host triad.