The rise of transplant oncology in primary liver cancer and metastatic disease - PubMed
6 hours ago
- #transplant oncology
- #liver transplantation
- #liver cancer
- Liver transplantation has expanded to include treatment for primary and metastatic liver malignancies.
- Transplant oncology is growing in importance for hepatocellular carcinoma, colorectal liver metastasis, neuroendocrine liver metastasis, and cholangiocarcinoma.
- Strategies to broaden eligibility and optimize donor organ use are emphasized.
- Downstaging approaches, such as locoregional therapies and systemic regimens, are key to meeting transplant criteria.
- Advances in donor utilization help expand the graft pool.
- Tailored immunosuppression balances graft protection with cancer control.
- Improved survival and reduced recurrence are seen with stringent patient selection and multimodal therapy.
- Transplant oncology is reshaping liver cancer treatment, supported by growing evidence.
- Collaboration between transplant and oncology disciplines is essential for standardized protocols.