ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice - PubMed
6 hours ago
- #ALKBH5
- #Male Infertility
- #Blood-Testis Barrier
- ALKBH5 promotes Srgn stability through m6A demethylation in high-fat diet mice.
- This process disrupts the integrity of the blood-testis barrier.
- The study links high-fat diet to male infertility via the spermatogenic microenvironment.
- Key elements involved include ALKBH5, N6-methyladenosine (m6A), and the blood-testis barrier.
- The research is supported by multiple national and institutional grants from China.