Multisite chronic pain and incident multiple sclerosis: A prospective cohort study - PubMed
6 hours ago
- #Inflammation
- #Chronic Pain
- #Multiple Sclerosis
- Chronic musculoskeletal pain was associated with a 26% increased risk of developing multiple sclerosis (MS) over a median 13-year follow-up.
- A dose-response relationship existed, where more pain sites correlated with higher MS risk; pain all over the body nearly quadrupled the risk.
- Systemic inflammation partially mediated the link between chronic pain and MS, suggesting shared neuroimmune pathways may underpin both conditions.