Direct conversion from alkenes to alkynes - PubMed
6 hours ago
- #selenanthrene reagent
- #organic chemistry
- #alkyne synthesis
- Alkynes are important in organic chemistry but converting alkenes to alkynes traditionally requires harsh conditions.
- A new recyclable selenanthrene reagent enables alkene desaturation to alkynes under mild conditions.
- This method is compatible with sensitive functional groups, allowing late-stage synthesis of complex alkynes.
- It also enables Z/E alkene configuration inversion, offering new possibilities for derivatization.