The gut microbiome and ageing trajectories: mechanisms and clinical implications - PubMed
12 hours ago
- #ageing
- #personalized medicine
- #gut microbiome
- The gut microbiome plays a key role in defining ageing patterns and age-related disease onset.
- The gut microbiome establishes lifelong dynamic interactions with the host via gut-organ axes.
- A 'normative' gut microbiome is elusive due to environmental interactions and high inter-individual variability.
- The causal role of the gut microbiome in ageing trajectories remains uncertain and may be context-specific.
- Multiparametric and uniqueness indexes can predict disability and mortality to some extent.
- Personalized strategies targeting the gut microbiome may help counteract age-related diseases and frailty.