[Conservative treatment of patients after peripheral arterial reconstruction for chronic critical limb ischemia] - PubMed
14 hours ago
- #anticoagulants
- #critical limb ischemia
- #vascular surgery
- Conservative management post-reconstructive vascular surgery is a key issue in modern medicine.
- Study evaluates aspirin and low-dose rivaroxaban efficacy/safety in atherosclerosis patients after lower limb arterial reconstruction.
- 182 patients (40-95 years) with chronic critical limb ischemia underwent femoropopliteal bypass surgery.
- Patients divided into 4 groups based on operation type and postoperative therapy.
- Follow-ups at 30 days, 3, 6, and 12 months via clinical exams and duplex ultrasound.
- Unfavorable outcomes (e.g., limb ischemia, amputation, thrombosis) varied by group (8.3%-24.4%).
- Major gastrointestinal bleeding occurred in 2.6% of one group, with no significant events in others.
- Low-dose rivaroxaban with aspirin was effective and safe compared to aspirin-clopidogrel post-revascularization.