Navigating through Neuropathic Pain: From Pathophysiology to Present and Future Treatments - PubMed
7 days ago
- #Emerging therapies
- #Neuropathic pain
- #Pain management
- Neuropathic pain (NP) arises from lesions or malfunctions in the somatosensory nervous system.
- NP lacks a universally accepted classification system or definitive biomarkers for diagnosis.
- It is categorized into peripheral and central neuropathic pain based on origin.
- Current treatments include anti-inflammatory drugs, anticonvulsants, antidepressants, and topical agents.
- Only less than 50% of patients achieve satisfactory relief with existing therapies.
- Novel therapies like cannabidiol (CBD) and advanced clinical interventions (e.g., spinal cord stimulation) are emerging.
- Regenerative therapies, including gene therapy, show promise for long-term NP alleviation.