Long-Term Exposure to Ambient Air Pollution and Incident Amyotrophic Lateral Sclerosis: A Prospective Cohort Analysis of the UK Biobank - PubMed
21 hours ago
- #Cohort Study
- #Amyotrophic Lateral Sclerosis
- #Air Pollution
- The study examined long-term exposure to ambient air pollutants (NO2, NOX, PM2.5, PM10) and the incidence of ALS in UK Biobank participants.
- No significant association was found between any of the pollutants and ALS risk, with hazard ratios close to 1 and confidence intervals including 1.
- Analyses included sensitivity checks, subgroup analyses, and tests for gene-environment interactions, all supporting the lack of association.
- The conclusion states that ambient air pollution was not a risk factor for ALS development in this large, prospective cohort study.