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The lactate-to-albumin ratio as a potential biomarker for short-term mortality risk in critically ill patients with urosepsis: a retrospective study with dual-cohort validation - PubMed

4 hours ago
  • #mortality risk
  • #biomarker
  • #urosepsis
  • The lactate-to-albumin ratio (LAR) is explored as a biomarker for short-term mortality risk in critically ill urosepsis patients.
  • The study used data from MIMIC-IV and an external validation cohort, analyzing 1,055 urosepsis patients.
  • Higher LAR was significantly associated with increased ICU and in-hospital mortality rates.
  • A non-linear positive dose-response relationship was found between LAR and mortality.
  • A risk model incorporating LAR and other variables showed superior predictive performance compared to traditional scores.
  • LAR is suggested as a cost-effective tool for early identification of high-risk urosepsis patients.