Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 - PubMed
4 hours ago
- #pediatrics
- #sepsis
- #guidelines
- Updated guidelines for managing sepsis and septic shock in children were issued by 68 international experts.
- The guidelines include 61 statements: 5 strong recommendations, 24 conditional recommendations, and 10 good practice statements.
- 20 recommendations are new, 13 updated for clarity or new evidence, 6 unchanged, and 22 carried forward due to lack of new evidence.
- Only three recommendations are based on high or moderate certainty of evidence.
- The panel used the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach to assess evidence quality.
- Conflict-of-interest policies were strictly applied, with many panel members disclosing financial ties to pharmaceutical and medical companies.