The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants - PubMed
5 hours ago
- #multicenter study
- #Fontan procedure
- #congenital heart disease
- The Fontan Outcomes Network is a learning health network involving 38 congenital heart centers in the US and Canada.
- A total of 1121 participants (mean age 16.3 years, 42% female) were enrolled in the study.
- Hypoplastic left heart syndrome (38.5%) and right ventricular-dominant anatomy (54.9%) were the most common diagnoses.
- Extracardiac conduit was the most frequent Fontan type (66.8%).
- 59% of cases experienced Fontan-related adverse events, including chylous pleural effusions (9.6%), Fontan thrombosis (7.1%), and nonperioperative stroke (6.5%).
- 41.3% of patients had a history of arrhythmia, increasing with age.
- 57.5% of patients had acquired comorbidities like asthma (12%) and sleep apnea (9%), with prevalence rising with age.
- Antithrombotic medication use was nearly universal, while other medications varied by age.
- 34.1% of patients had a clinical diagnosis of an anxiety disorder, with 48.1% of adults affected.
- The study highlights the mental health needs of this population, with 11.8% of patients prescribed antidepressants.