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Association of Peripheral Inflammatory Indices With Symptom Severity, Functioning, and Metabolic Parameters in the Mexican Population Diagnosed With Schizophrenia - PubMed

6 hours ago
  • #Metabolism
  • #Inflammation
  • #Schizophrenia
  • Study examined associations between peripheral inflammatory indices (PIIs) and clinical/metabolic parameters in 100 clinically stable Mexican patients with schizophrenia.
  • No significant correlations found between PIIs (including NLR, MLR, PLR, SII, SIRI, AISI) and symptom severity (PANSS), functioning (FAST), or depression (CDSS).
  • Weak positive correlations observed between glycemic control (HbA1c) and systemic inflammatory indices (SII, AISI, SIRI).
  • Weak negative correlations identified between triglyceride levels and several PIIs (NLR, MLR, PLR, SII).
  • Findings suggest PIIs are linked to metabolic impairments (glycemic and triglyceride alterations) rather than symptom severity or functioning in clinically stable schizophrenia patients.