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Effect of Vitamin C on the Prognosis of Patients with Acute Pancreatitis-Related Acute Kidney Injury Admitted to the Intensive Care Unit: A Retrospective Study - PubMed

5 hours ago
  • #Vitamin C
  • #Acute Kidney Injury
  • #ICU Prognosis
  • Vitamin C administration is associated with reduced 30-day mortality in ICU patients with acute pancreatitis-related acute kidney injury (AP-AKI).
  • The study is a retrospective analysis using the MIMIC-IV database, employing propensity score matching to control for confounders.
  • Subgroup analysis suggests potential heterogeneity in the effect of Vitamin C among patients aged ≥65 and those with myocardial infarction.
  • Different doses of Vitamin C did not show a significant difference in 30-day mortality outcomes for AP-AKI patients.
  • The research concludes that Vitamin C may improve prognosis in AP-AKI, but dose variations do not impact mortality.