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New-Onset Atrial Fibrillation and Accelerated Kidney Function Decline in Working-Age Adults - PubMed

3 hours ago
  • #Kidney Function Decline
  • #Atrial Fibrillation
  • #Working-Age Adults
  • New-onset atrial fibrillation (AF) in working-age adults is associated with a faster annual decline in estimated glomerular filtration rate (eGFR) compared to those without AF.
  • The study found a difference of -0.29 mL/min/1.73 m² per year in eGFR decline between those with new-onset AF and those without.
  • New-onset AF was linked to a significantly higher risk of a 30% or greater decline in eGFR, with a hazard ratio of 2.91.
  • This retrospective cohort study analyzed health screening and insurance data from Japan, involving matched participants aged 35 to 59 years.
  • Further research is needed to understand the impact of AF burden and the effectiveness of AF treatments on kidney outcomes.