Dietary vitamin e intake, life expectancy, and mortality risk among adults in the United Kingdom and the United States - PubMed
3 days ago
- #mortality
- #life expectancy
- #vitamin E
- Study explores the impact of dietary vitamin E intake on all-cause mortality, cause-specific mortality, and life expectancy.
- Participants included 12,977 from US NHANES and 70,369 from UK Biobank, divided into tertiles based on vitamin E intake.
- Highest tertile in US NHANES had 32% lower mortality risk; UK Biobank highest tertile had 7% lower risk.
- Significant association between vitamin E intake and CVD mortality in US NHANES, but not in UK Biobank.
- Highest tertile in US NHANES with diabetes, CVD, or hypertension had 33-35% lower all-cause mortality risk.
- UK Biobank highest tertile showed 13% lower risk for CVD and 9% for hypertension-related mortality.
- Non-linear threshold effects observed, with changepoints at 6.7-13.7 mg/day (UK) and 4.8-37.0 mg/day (US).
- 3.650-10.29% of all-cause mortality could be attributed to low dietary vitamin E intake.
- Participants with underlying conditions showed significant increase in life expectancy with higher vitamin E intake.
- Higher dietary vitamin E intake associated with lower all-cause mortality, stronger in US than UK cohort.
- Protective effects of vitamin E concentrated within an optimal intake range, not increasing indefinitely.