Association between estimated glucose disposal rate and incident heart failure in patients with coronary heart disease: a prospective cohort study - PubMed
5 hours ago
- #Coronary Heart Disease
- #Insulin Resistance
- #Heart Failure
- eGDR is a composite index for insulin resistance and is linked to incident heart failure in coronary heart disease patients.
- In a study of 20,329 CHD patients, each 1-unit increase in eGDR was associated with a 51% reduced risk of heart failure.
- eGDR showed superior predictive ability for HF risk compared to other insulin resistance indices, with an AUC of 0.612.
- Trajectory analysis indicated that eGDR levels were consistently low up to 15 years before HF onset in affected individuals.
- The findings suggest eGDR could serve as an early predictor for heart failure in patients with coronary heart disease.