Prenatal Exposure to Mixtures of Nonpersistent Endocrine-Disrupting Chemicals and Angiogenic Biomarkers, Placental Function, and Fetal Growth - PubMed
14 hours ago
- #prenatal exposure
- #fetal growth
- #endocrine-disrupting chemicals
- Prenatal exposure to nonpersistent endocrine-disrupting chemicals (EDCs) may impact placental function and fetal growth.
- The study involved 734 pregnant participants from the Barcelona Life Study Cohort (BiSC), Spain (2018-2021).
- Exposure to low-molecular-weight phthalates (LMWP) was associated with decreased birthweight z-scores and altered fetoplacental hemodynamics.
- Organophosphate exposure was linked to increased birthweight z-scores.
- Angiogenic biomarkers mediated the relationship between LMWP exposure and reduced birthweight.
- The study highlights the role of chemical mixtures in influencing fetal growth and placental function.