Raising strong yeast as a petroleum substitute
a day ago
- #yeast
- #biotechnology
- #sustainability
- Mutated baker’s yeast (Saccharomyces cerevisiae) is being developed as an alternative for petroleum in 2,3-butanediol (2,3-BDO) production.
- Researchers at Osaka Metropolitan University enhanced yeast tolerance to 2,3-BDO by introducing genomic mutations, resulting in a strain (YPH499/Co58) that proliferates 122 times more than the parent strain.
- Gene expression analysis revealed that proteasome, peroxisome, TCA cycle, mitochondria, and transcriptional regulation genes play a key role in 2,3-BDO tolerance.
- This method could support sustainable production of 2,3-BDO and other useful compounds, aligning with green initiatives.
- The study was published in Applied Microbiology and Biotechnology and funded by the GteX Program of Japan.