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Factors associated with early complete resolution after radiofrequency ablation for low-risk papillary thyroid microcarcinoma: a dual-center retrospective study - PubMed

4 days ago
  • #Thyroid carcinoma
  • #Radiofrequency ablation
  • #Ultrasonography
  • Study identifies predictors of early complete resolution (within 1 year) after radiofrequency ablation (RFA) for low-risk papillary thyroid microcarcinoma (PTMC).
  • Cumulative complete resolution rates were 62.2% at 1 year and 98.7% at 2 years.
  • Independent predictors of complete resolution within 1 year include normal thyroglobulin antibody (TgAb) and thyroid peroxidase antibody (TPOAb) levels, nodule diameter ≤ 5 mm, and absence of intratumoral vascularity.
  • Energy density showed an inverted U-shaped relationship with resolution probability within 1 year.
  • Findings suggest RFA achieves favorable long-term efficacy for low-risk PTMC, with early resolution predictable by specific factors.
  • The study provides insights for refining RFA techniques and developing personalized follow-up strategies.