Small RNA-directed DNA methylation by Pol IV and Pol V maintains immune homeostasis in soybean - PubMed
12 hours ago
- #Epigenetics
- #Plant Immunity
- #DNA Methylation
- Small RNA-directed DNA methylation (RdDM) by Pol IV and Pol V is crucial for immune homeostasis in soybean.
- RdDM prevents premature activation of immune response genes, including NLRs and EDS1 pathway components.
- Pol IV and Pol V mutants show loss of DNA methylation and constitutive immune gene activation, leading to autoimmunity.
- RdDM-mediated epigenetic regulation is dynamically adjusted in response to pathogen exposure.
- The study highlights RdDM as a regulatory mechanism to fine-tune plant immune responses.