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The Associations of Anthropometric Indices With Stages and Mortality in Cardiovascular-Kidney-Metabolic Syndrome: Insights From NHANES - PubMed

5 days ago
  • #anthropometry
  • #mortality
  • #CKM syndrome
  • Study explores the link between anthropometric indices and Cardiovascular-Kidney-Metabolic (CKM) syndrome stages and mortality.
  • Data from NHANES (1999-2018) analyzed, involving 28,911 adults categorized into CKM stages 1-2 and 3-4.
  • Key findings show body mass index, waist circumference, Weight-adjusted Waist Index (WWI), and relative fat mass increase with CKM severity.
  • Higher quartiles of A Body Shape Index (ABSI), WWI, waist-to-height ratio (WHtR), and Conicity Index (C-index) linked to increased mortality in early CKM stages.
  • ABSI and WWI consistently associated with mortality in advanced CKM stages (3-4).
  • ABSI, WWI, and C-index showed the best discrimination for CKM progression.
  • Central adiposity measures (like ABSI, WWI) more strongly associated with CKM outcomes than general adiposity measures.
  • Findings suggest potential for anthropometric indices in early risk stratification and targeted interventions for CKM syndrome.