Beyond the 2024 McDonald criteria for defining and diagnosing multiple sclerosis - PubMed
5 hours ago
- #Diagnostic Criteria
- #Medical Research
- #Multiple Sclerosis
- The multiple sclerosis community has improved diagnostic criteria by incorporating new technology and recognizing the need for early diagnosis.
- Current diagnostic criteria's performance in clinical practice is uncertain, necessitating a new approach to enhance sensitivity and specificity.
- A tiered process is proposed for developing and validating future diagnostic criteria, underpinned by a biological definition of MS.
- The MS community is recommended to initiate a prospective international study to validate and compare diagnostic criteria.
- The goal is to improve diagnostic accuracy and identify individuals with early biological disease, possibly without relying on clinical or radiological confirmation.