Preclinical and clinical obesity: prevalence, associations to cardiometabolic risk and response to lifestyle intervention in NHANES and the EPIC-Potsdam and TULIP studies - PubMed
a day ago
- #obesity
- #lifestyle intervention
- #cardiometabolic risk
- Novel diagnostic criteria distinguish between preclinical and clinical obesity, with treatment indications for clinical obesity.
- In NHANES 2017-2018 and EPIC-Potsdam cohort, 100% of BMI-based obesity cases were confirmed by another anthropometric measure.
- Over 80% of adults with confirmed obesity meet clinical obesity criteria, showing 2.8-fold higher cardiovascular disease risk and 7.9-fold higher type 2 diabetes risk compared to non-obese adults.
- Adults with preclinical obesity have no elevated cardiovascular disease risk but significantly increased type 2 diabetes risk.
- A 9-month lifestyle intervention reduced clinical obesity prevalence from 71% to 57% and prediabetes from 52% to 29%.