Extracellular GPX4 functions as an immunosuppressive DAMP in ferroptosis - PubMed
6 hours ago
- #GPX4
- #ferroptosis
- #immunosuppression
- Extracellular GPX4 acts as an immunosuppressive damage-associated molecular pattern (DAMP) during ferroptosis.
- It impairs antitumor immunity by interacting with dendritic ZP3 receptors.
- The authors declare no competing interests, and the findings are linked to a specific study on this mechanism in cancer immunity.