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A septal inhibitory circuit constrains alcohol reward and mediates liraglutide's suppressive effects on alcohol intake in mice - PubMed

5 hours ago
  • #liraglutide
  • #alcohol reward
  • #GLP-1R
  • GLP-1R signaling in the dorsal lateral septum regulates alcohol consumption and reward.
  • Liraglutide reduces alcohol intake and dopamine release via GLP-1R in the dorsal lateral septum.
  • A local inhibitory circuit from dorsal to ventral lateral septum modulates alcohol-related behaviors.