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GLP-1 and dual GIP/GLP-1 agonists in obese patients with HFpEF: a systematic review and meta-analysis of RCTs - PubMed

5 hours ago
  • #GLP-1 agonists
  • #meta-analysis
  • #HFpEF
  • Systematic review and meta-analysis examined GLP-1 and dual GIP/GLP-1 agonists in obese patients with HFpEF (heart failure with preserved ejection fraction).
  • Focus on efficacy, noting that these agonists may improve outcomes in heart failure with mildly reduced or preserved ejection fraction.
  • Involves assessment of risk of bias using RoB 2 tool, following PRISMA 2020 guidelines for reporting.
  • Studies include references to semaglutide and tirzepatide as examples of agonists used.
  • Authors declared no competing interests, with ethics approval not required due to use of published data.