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Inflammatory CADASIL: the cross-link between CADASIL and multiple sclerosis: a report of two cases and systematic review of the literature - PubMed

5 hours ago
  • #Multiple Sclerosis
  • #Neuroimmunology
  • #CADASIL
  • CADASIL patients can be misdiagnosed with multiple sclerosis (MS).
  • A systematic review identified 19 cases with CADASIL and MS-like inflammatory features.
  • Common features include sensory and motor manifestations, gait imbalance, and migraine.
  • Most patients had small vessel disease or demyelinating lesions on imaging.
  • Genetic testing is crucial for accurate diagnosis in suspected CADASIL cases.
  • The term 'inflammatory CADASIL' is proposed for such presentations.