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Automatic acromegaly detection using deep learning on hand images: a multicenter observational study - PubMed

5 hours ago
  • #deep learning
  • #medical imaging
  • #acromegaly
  • Development of a privacy-conscious deep learning model for detecting acromegaly using hand images.
  • Study involved 716 patients (317 with acromegaly and 399 controls) and 11,480 images from 15 Japanese pituitary centers.
  • Hand images focused on the dorsal and fist sign, excluding palm/fingerprint regions, were used.
  • Model achieved high performance metrics: sensitivity of 0.89, specificity of 0.91, and AUC of 0.96.
  • Outperformed endocrinologists with F1-scores ranging from 0.43 to 0.63.
  • Highlights utility of dorsal hand and fist sign as diagnostic clues for acromegaly.
  • Potential deployment in public settings like health checkups due to privacy-conscious features.
  • Further validation needed with larger datasets including healthy individuals and diverse diseases.