Long-Term Outcomes of Concurrent Chemoradiotherapy With S-1 in Older Patients With Esophageal Cancer: A Secondary Analysis of a Randomized Clinical Trial - PubMed
6 hours ago
- #elderly patients
- #esophageal cancer
- #chemoradiotherapy
- The study evaluated long-term outcomes of concurrent chemoradiotherapy (CCRT) with S-1 versus radiotherapy (RT) alone in older patients (aged 70–85 years) with esophageal cancer.
- CCRT with S-1 showed significantly improved overall survival (median OS 24.7 months vs. 15.1 months) and progression-free survival (median PFS 18.7 months vs. 9.2 months) compared to RT alone.
- No increased noncancer-related mortality was observed with CCRT, supporting its use as a preferred regimen for this elderly patient population.