[Optimal timing for octreotide administration in adult patients with chylothorax: A scoping review] - PubMed
6 hours ago
- #Chylothorax
- #Octreotide Timing
- #Scoping Review
- Octreotide is used to treat chylothorax, a rare condition causing malnutrition, dehydration, and respiratory failure.
- The scoping review found no consensus on the optimal timing for starting octreotide therapy.
- Studies reviewed included doses from 150 to 300 µg/day, mostly subcutaneous, with treatment durations ranging from 1 to 16 days.
- Efficacy rates varied widely, from 48.9% to 100%, but no studies directly answered the research question.
- Most patients were male with a mean age of 48 to 67.5 years, and the evidence was limited to six studies.
- Prospective studies or clinical trials are recommended to establish standardized timing, dosage, and duration for safer practice.